02 Oct
Despite years of success in lowering lead exposure, researchers say the toxic metal is still a main source of elevated blood lead levels in children.
Clinical trials sponsored by Big Pharma enrolled eight times as many patients as U.S.-government trials did between 2018 and 2022, new research shows.
The study -- conducted by researchers at Fred Hutch Cancer Center in Seattle -- underscores the lack of investment in fe...
Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies.
Only 5% of therapies tested in animals wind up being approved by regulators f...
Black and Hispanic patients with Alzheimer's disease are greatly underrepresented in clinical trials, even though they're more likely to get dementia than whites.
However, racial discrimin...
More patients these days are taking part in cancer research, a new study finds.
At least one in five people with cancer (22%) participate in some form of clinical research, when all types of cancer studies are considered, researchers found.
Moreover, enrollment in ...
For people with tough-to-treat epilepsy, seizures can be both frightening and dangerous, but a new experimental pill may bring significant relief to over one-third of them.
Dubbed XEN1101, the new drug reduced the frequency of seizures by more than 50%, or even eliminate...
A nasal spray containing a ketamine derivative appears to beat one of the standard drugs used for people with difficult-to-treat depression, a new clinical trial has found.
The trial, of nearly 700 people with treatment-resistant depression, found that esketamine nasal s...
People with type 1 diabetes lack functional islet cells in their pancreas to produce the hormone insulin and must take daily insulin via injections or a continuous pump to compensate.
Every day, millions of people must take one or more pills to control their blood pressure and reduce their risk for heart attack or stroke, but if new research pans out, some may be able to scrap their pills for a twice-yearly shot with the same benefits.
Given as a shot...
Another experimental drug meant to slow the damage of Alzheimer's appears poised to join a growing arsenal of new treatments for this memory-robbing disease.
Low doses of the eyedrops ophthalmologists use to dilate your pupils during an eye exam are not able to slow the progression of nearsightedness (myopia) in children, a new clinical trial has found.
Atropine eyedrops at a concentration of 0.01% did not outperform placebo ...
The U.S. Food and Drug Administration on Thursday gave full approval to the Alzheimer's drug Leqembi, clearing the way for insurance coverage of the pricey drug.
"The full FDA approval will open the floodgates for people with early Alzheimer's to get this drug. It's a bi...
An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows.
Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, duri...
Patients with bile duct cancer might soon have an additional treatment available to them, thanks to a newly discovered tumor target.
Some bile duct cancers are driven by a mutated HER2 gene, which has also been implicated in cancers of the breast, esophagus and prostate,...
A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.
Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positi...
A safe, generic diabetes pill can help people avoid long COVID, a new clinical trial shows.
Metformin cut the risk of long COVID by about 40% for patients who received a two-week course of the drug while battling their infection, the researchers reported.
The ...
For years, doctors have thought that a more extensive surgery that removes a wider swath of lymph nodes was the best option for certain patients with bladder cancer. Now, a new clinical trial is upending that belief.
Researchers found that the strategy -- known as exten...
Once-a-day use of the targeted cancer pill Tagrisso (osimertinib) cut the five-year death rate in half for a subset of patients with early-stage lung cancer, a new clinical trial shows.
The results could have major implications for patients whose cancers carry a mutation...
A new study on using nitroglycerin patches to help women with frequent hot flashes caused by menopause has delivered mixed results.
The benefits of wearing these patches -- long used as chest pain medication -- were modest. They also were short-lived, with any benefits ...
An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.
The oral drug vorasidenib nearly tripled progression-free survival in patients with grade 2 gliomas compared to placebo, nearly 28 months...
A new liver dialysis device might soon be able to save patients on the edge of death from liver failure, early clinical trial results show.
The DIALIVE device safely improved organ function and alleviated symptoms in patients with acute-on-chronic liver failure, compared...
A common test for lung function may be missing lung problems in Black men, leading to under-diagnosis and insufficient care.
A new study from the University of Pennsylvania estimates that as many as 40% more Black male patients would have been diagnosed with breathing ...
An extended-release version of a Parkinson's disease drug could provide more stable relief for patients with the movement disorder, new clinical trial data show.
The new formulation of levodopa, called IPX203, extended the duration of patients' "on time" -- the amount of...
Whether the gender of a blood donor could affect the recipient's survival was an unanswered question in medicine. Until now.
"Some observational studies had suggested female donor blood might be linked with a higher risk of death among recipients compared to male donor b...
An experimental targeted drug could provide a fresh chance for people with recurring head and neck cancer that has grown resistant to other treatments, a new clinical trial says.
Ficlatuzumab used in combination with the already approved targeted drug cetuximab (Erbitux)...
An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials.
Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds at all af...
Cynthia Elford had recently lost her left leg to type 1 diabetes, after a sunburned big toe turned nearly black and forced an amputation.
Now, Elford was being told the same thing was happening in her right leg.
"I went to clip the toenail on the big toe of my righ...
Patients could soon have access to a new injectable drug to treat atopic dermatitis, the most common form of eczema.
The drug, lebrikizumab, proved effective in teenagers and adults in two clinical trials just published in the
A new study is raising questions about the effectiveness of medications long used to prevent painful kidney stones, but experts say there's no reason for patients to toss their prescriptions out at this point.
Anyone who has ever passed a kidney stone would prefer to avo...
Using a "neuroprotectant" drug alongside the standard surgical removal of a clot may slash the risk of death and disability following a stroke, a new study finds.
The new medication, called ApTOLL, shields brain tissue from continuing damage by cooling down inflamma...
A single injection of an experimental biologic drug may cut in half your risk of hospitalization from COVID-19 infection, new clinical trial results show.
Pegylated lambda interferon (PEG-lambda) proved effective against all COVID-19 variants encountered in this internat...
The best treatment for a genetically driven form of lung cancer continues to show lasting benefits, a new clinical trial update shows.
Tagrisso (osimertinib) nearly doubles disease-free survival in earlier-stage patients whose lung cancer is driven by a mutation in their...
The U.S. Food and Drug Administration on Friday approved a second Alzheimer's drug, lecanemab, despite reports of rare brain bleeds linked to use of the drug in some patients.
However, the FDA pointed to the drug's benefits, as well.
"Alzheimer's disease immeasura...
Lecanemab: It's an experimental medication that's been shown in trials to slow cognitive decline in people with Alzheimer's disease.
It's also up for accelerated approval by the U.S. Food and Drug Administration, with a decision expected by Jan. 6.
However, the d...
A relatively new drug is boosting survival rates for women with a specific type of advanced breast cancer who haven't responded to other treatments, according to a pair of clinical trials.
The targeted antibody drug -- trastuzumab deruxtecan (T-DXd, sold under the b...
Two people have now died from brain hemorrhages that may be linked to an experimental Alzheimer's drug, calling into question the medication's safety.
A 65-year-old woman with early-stage Alzheimer's recently died from a massive brain bleed that some researchers link to ...
Infants and children sick with RSV are flooding pediatricians' offices and children's hospitals across the United States, due to an early surge of the common childhood virus this year.
But within one or two "sick seasons,"doctors expect to have on hand long-sought tools ...
New drugs that could slow or prevent the start of dementia would be groundbreaking, but a new poll suggests many middle-aged adults may be reluctant to take part in the studies that test those medications.
Only about 12% of the roughly 1,000 people aged 50 to 64 who were...
Flash radiotherapy, a new technology that uses targeted proton beams, is safe and effective in relieving pain for terminal cancer patients, a new, small study suggests.
...
The ability of TPOXX to treat people infected with monkeypox is being directly tested in a new clinical trial in central Africa, U.S. health officials have announced.
TPOXX -- th...
Researchers report early success with using an existing rheumatoid arthritis (RA) drug to treat systemic sclerosis, a rare but potentially devastating autoimmune condition.
Th...
Larry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.
Japanese drugmaker Eisai on Wednesday said its experimental drug lecanemab helped slow thinking declines among people in the early stages of Alzheimer's disease.
The findings from a phase 3...
A frequently used screening test for autism creates a gender gap that could hinder diagnosis an...
An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain.
Affecting as many as 1.5 million people in the United States, lupus is an autoimmun...
An experimental antibody therapy for multiple sclerosis can cut symptom flare-ups by half, versus a standard treatment, a new clinical trial has found.
The drug, called ublituximab, be...
An experimental new pill could boost treatment of the autoimmune disease lupus, researchers reported at the American Chemical Society's annual meeting.
The pill has been shown in mouse studies to inhibit lupus symptoms, reverse signs of organ damage, and prevent death, <...
To ensure that all kinds of patients get drugs and devices that are safe and effective for them, they need to be represented in clinical trials, but a new study shows that
Cancer clinical trials in the United States appear to be rebounding after a significant slowdown during the pandemic, researchers say.
For the study, the investigators analyzed da...
A newly approved drug for type 2 diabetes may be a game-changer for treating obesity, too.
Given as a shot once a week, tirzepatide works on two naturally occurring hormones that help tell the brain that you are full. It may be as effective as weight-loss surgery.
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A small study delivers startling results on the power of a new immunotherapy treatment against rectal cancer: The drug triggered remission in all the patients who got it.
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